- Checkpoint Mutants
- mad2∆
- bub2∆
- mad2∆ bub2∆
- cdc20-ts mad2∆
- cdc20-ts bub2∆
- WT in nocodazole
- mad2∆ in nocodazole
- mad2∆ GAL-TEM1 in nocodazole
- mad2∆ pds1∆ in nocodazole
- bub2∆ in nocodazole
- bub2∆ pds1∆ in nocodazole
- bub2∆ mad2∆ in nocodazole
- pds1∆ in nocodazole
- net1-ts in nocodazole
cdc20-ts bub2∆
debug: ,
test user =
test db =
Simulation:
Change of parameters: ks20'=ks20"=0, kbub2=0, init BUB2=0.
Length of G1 phase: 43.1 min.
Arrest: Metaphase arrest.
Experiments:
Shirayama, M., Zachariae, W., Ciosk, R. and Nasmyth, K. (1998). The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae. EMBO J. 17:1336-1349.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Fig. 8, metaphase arrest, as cdc20-ts.
Comments:
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